Listar Departamento de Ciencias Médicas y Quirúrgicas por título
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Retinal and Choroidal Effects of Continuous Positive Airway Pressure as Treatment for Sleep Apnea: Results at 12 Months
(MDPI, 2022)Background: To determine the impacts of continuous positive airway pressure (CPAP) treatment on retinal and choroidal thickness measurement in individuals with obstructive sleep apnea (OSA). Methods: Participants were 28 ... -
Riesgo de infección y mortalidad en pacientes colonizados por Klebsiella pneumoniae productora de KPC: validación de scores y propuesta de manejo
(Universidad de Córdoba, UCOPress, 2023)Con este trabajo hemos pretendido optimizar los criterios de tratamiento empírico apropiado en pacientes colonizados por KPCKP, con signos y síntomas de infección, así como conocer si existe un periodo de tiempo donde se ... -
Right Ventricular Function in long-term survivors of childhood acute Lymphoblastic Leukemia: from the CTOXALL study
(MDPI, 2023)There are limited data regarding right ventricle (RV) impairment in long-term survivors of childhood acute lymphoblastic leukemia (CLS). The aim of this study was to assess RV function in these patients using echocardiographic ... -
Role of nitric oxide in the biology of intestinal cancer stem cells: new options in the treatment of colorectal cancer
(Universidad de Córdoba, UCOPress, 2018)Nitric oxide (NO) has been highlighted as an important agent in cancer-related events. Although the inducible nitric oxide synthase (iNOS) isoform has received most of the attention, recent literature indicates that the ... -
Seguimiento a largo plazo de pacientes con miocardiopatía dilatada idiopática tras infusión intracoronaria de células de médula ósea
(Universidad de Córdoba, UCOPress, 2016)Las enfermedades cardiovasculares, y dentro de ellas la insuficiencia cardíaca (IC), son unas de las causas más frecuentes de morbimortalidad en el primer mundo. La principal causa de IC sigue siendo la cardiopatía isquémica, ... -
Sirolimus tópico en el tratamiento de angiofibromas faciales asociados a esclerosis tuberosa
(Universidad de Córdoba, UCOPress, 2016)El complejo de la esclerosis tuberosa (TSC) es un raro trastorno neurocutáneo de trasmisión autosómico dominante que se caracteriza por el desarrollo de tumoraciones hamartomatosas multisistémicas1. Dentro de las manifestaciones ... -
Study of the alterations of mineral metabolism and bone disorders associated with chronic kidney disease
(Universidad de Córdoba, UCOPress, 2019)Chronic Kidney Disease (CKD) affects million people worldwide and is a risk factor for morbidity and mortality. CKD patients have poor bone mineral density due to mineral metabolism imbalance and secondary hyperparathyroidism ... -
Subclinical Atherosclerosis Measure by Carotid Ultrasound and Inflammatory Activity in Patients with Rheumatoid Arthritis and Spondylarthritis
(MDPI, 2022)Objective: To compare the effect of inflammation on subclinical atherosclerosis using carotid ultrasound in patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA). Methods: Cross-sectional study including 347 ... -
Targeting metabolism to improve immunotherapy in gsnor-deficient colorectal cancer
(Universidad de Córdoba, UCOPress, 2024)Colorectal cancer (CRC) is the third most diagnosed type of cancer and the second leading cause of cancer death worldwide. Despite the increasing knowledge of CRC molecular biology and the development of new targeted ... -
Telomere maintenance is associated with type 2 diabetes remission in response to a long-term dietary intervention without non-weight loss in patients with coronary heart disease: from the CORDIOPREV randomized controlled trial
(MDPI, 2024)In order to evaluate whether telomere maintenance is associated with type 2 diabetes remission, newly diagnosed type 2 diabetes patients without glucose-lowering treatment (183 out of 1002) from the CORDIOPREV study ... -
Terapia antiangiogénica en cáncer colorrectal metastásico: identificación de biomarcadores
(Universidad de Córdoba, UCOPress, 2022) -
Terapia celular en el tratamiento de la miocardiopatía dilatada idiopática
(Universidad de Córdoba, UCOPress, 2015)Las miocardiopatías dilatadas (MCD) idiopáticas se definen como enfermedades del músculo cardiaco caracterizadas por las alteraciones en el tamaño de las cámaras cardíacas, en el grosor de la pared ventricular, o por una ... -
Técnica de la guía encarcelada en el tratamiento percutáneo de las bifurcaciones coronarias con stents: estudio aleatorrizado con microscopía estereoscopica
(Universidad de Córdoba, Servicio de Publicaciones, 2016)El tratamiento percutáneo de las lesiones coronarias en bifurcación constituye uno de los procedimientos terapéuticos de mayor complejidad técnica dentro de la cardiología intervencionista. El desarrollo de nuevas técnicas ... -
TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
(Public Library of Science, 2014)Background: Transforming growth factor-b (TGF-b) is a key cytokine during differentiation of mesenchymal stem cells (MSC) into vascular smooth muscle cells (VSMC). High phosphate induces a phenotypic transformation of ... -
The APOB -516C/T polymorphism has no effect on lipid and apolipoprotein response following changes in dietary fat intake in a healthy population
(Elsevier, 2007)Our goal was to determine whether the presence of the −516C/T polymorphism in the APOB gene promoter modifies the lipid response to changes in the amount and quality of dietary fat. We studied 97 young healthy volunteers ... -
The Apolipoprotein E Gene Promoter (−219G/T) Polymorphism Determines Insulin Sensitivity in Response to Dietary Fat in Healthy Young Adults
(Elsevier, 2005)Insulin sensitivity (IS) is determined by genetic and environmental factors, including diet. The apoE gene promoter −219G/T polymorphism is associated with coronary heart disease and increased postprandial triacylglycerol-rich ... -
The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast
(Wiley, 2022)Objectives: (1) To evaluate clinical and molecular cardiovascular disease (CVD) signs and their relationship with psoriatic arthritis (PsA) features and (2) to identify a clinical patient profile susceptible to benefit ... -
The Combination of Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio with Liquid Biopsy Biomarkers Improves Prognosis Prediction in Metastatic Pancreatic Cancer
(MDPI, 2021)Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a highly inflammatory microenvironment and liquid biopsy has emerged as a promising tool for the noninvasive analysis of this tumor. In this study, plasma ... -
The dysbiosis of the bacterial population of the digestive system (intestinal microbiota) in patients with metabolic syndrome improves after two models of healthy diets: a diet rich in complex carbohydrates and a Mediterranean diet. CORDIOPREV study
(Universidad de Córdoba, UCOPress, 2017)The microbial community harbored in the human intestine, commonly known as the gut microbiota, is considered an organ fully integrated in the host which plays an important role in metabolism, physiology, nutrition and ... -
The Effect of Dietary Fat on LDL Size Is Influenced by Apolipoprotein E Genotype in Healthy Subjects
(American Society for Nutrition, 2004)LDL particle size is dependent on both genetic factors and environmental factors such as dietary fat composition. The apolipoprotein E (apoE) genotype is a major genetic determinant of LDL size. Thus, the aim of this work ...