Listar DBCFI-Artículos, capítulos... por autor "03a50ce6-338b-441b-9033-068bc0d32f8e"
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Los ASPECTOS INMUNOLÓGICOS de la respuesta al virus SARS-CoV-2 responsable de la enfermedad denominada COVID-19
Solana Lara, Rafael (Universidad de Córdoba, 2020) -
Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia
Valhondo, Isabel; Hassouneh, Fakhri; López-Sejas, Nelson; Pera Rojas, Alejandra; Sánchez-Correa, Beatriz; Guerrero, Beatriz; Bergua, Juan M.; Arcos, María José; Bañas, Helena; Casas-Avilés, Ignacio; Sánchez García, Joaquín; Serrano, Josefina; Martín, Carmen; Durán, Esther; Alonso, Corona; Solana Lara, Rafael; Tarazona, Raquel (MDPI, 2020)Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ... -
CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals
Pera Rojas, Alejandra; Campos Fernández, Carmen; Sánchez-Correa, Beatriz; Tarazona, Raquel; Larbi, Anis; Solana Lara, Rafael; Alonso, Corona (Public Library of Science, 2014)Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in ... -
Diseño de una nueva asignatura dirigida al aprendizaje, integración y evaluación de competencias transversales en el grado de Medicina para la aplicación y mejora de su perfil laboral
Solana Lara, Rafael; Jiménez Reina, L.; Labella Quesada, Fernando; Peña Amaro, J. (Consejo Social de la Universidad de Córdoba, 2012)La propuesta presenta la creación de una nueva asignatura en el grado de Medicina: Aplicación Clínica de las Ciencias Médicas Básicas –cuyo desarrollo ha implicado una inversión de 6.000 euros– que se imparte en el ... -
DNAM-1 and the TIGIT/PVRIG/TACTILE Axis: Novel Immune Checkpoints for Natural Killer Cell-Based Cancer Immunotherapy
Sánchez-Correa, Beatriz; Valhondo, Isabel; Hassouneh, Fakhri; López-Sejas, Nelson; Pera Rojas, Alejandra; Bergua, Juan M.; Arcos, María José; Bañas, Helena; Casas-Avilés, Ignacio; Durán, Esther; Alonso, Corona; Solana Lara, Rafael; Tarazona, Raquel (MDPI, 2019)Natural killer (NK) cells are lymphocytes of the innate immune response characterized by their role in the destruction of tumor cells. Activation of NK cells depend on a fine balance between activating and inhibitory signals ... -
Effect of Cytomegalovirus (CMV) and Ageing on T-Bet and Eomes Expression on T-Cell Subsets
Hassouneh, Fakhri; López-Sejas, Nelson; Sánchez-Correa, Beatriz; Tarazona, Raquel; Solana Lara, Rafael; Pera Rojas, Alejandra; Campos Fernández, Carmen (MDPI, 2017)The differential impact of ageing and cytomegalovirus (CMV) latent infection on human T-cell subsets remains to some extent controversial. The purpose of this study was to analyse the expression of the transcription factors ... -
Functional Changes of T-Cell Subsets with Age and CMV Infection
Hassouneh, Fakhri; Goldeck, David; Pera, Alejandra; Heemst, Diana van; Slagboom, P. Eline; Pawelec, Graham; Solana Lara, Rafael (MDPI, 2021)Cytomegalovirus (CMV) latent infection and aging contribute to alterations in the function and phenotype of the T-cell pool. We have demonstrated that CMV-seropositivity is associated with the expansion of polyfunctional ... -
Immune Checkpoint Inhibitors for Vaccine Improvements: Current Status and New Approaches
Batista-Duharte, Alexander; Hassouneh, Fakhri; Álvarez-Heredia, Pablo; Pera, Alejandra; Solana Lara, Rafael (MDPI, 2022)In recent years, the use of immune checkpoint inhibitors (ICIs) in combination with approved or experimental vaccines has proven to be a promising approach to improve vaccine immunogenicity and efficacy. This strategy seeks ... -
El uso de redes sociales como instrumento innovador en la educación universitaria: Facebook como herramienta de aprendizaje colaborativo en la asignatura de Inmunología
Calzado Canale, Marco Antonio; Muñoz Blanco, Eduardo; Solana Lara, Rafael; Santamaría Ossorio, Manuel; Peña Martínez, José; Lara Chica, M. Isabel; Cantarero, Irene; Pera Rojas, Alejandra; Campos Fernández, Carmen; Ortega Gromaz, Consuelo (UCOPress, 2018)En la actualidad los docentes universitarios tienen el reto de enseñar a la conocida como “generación Y”, alumnos nacidos entre los años 1980 y 2000, los cuales no han conocido el mundo sin internet o teléfono móvil. Esto ...