Departamento de Biología Celular, Fisiología e Inmunología
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Changes in quantity plant‑based protein intake on type 2 diabetes remission in coronary heart disease patients: from the CORDIOPREV study
(Springer, 2023)Purpose: Diabetes remission is a phenomenon described in the context of drastic weight loss due to bariatric surgery or low-calorie diets. Evidence suggests that increasing the intake of plant protein could reduce the risk ... -
Intravascular hemolysis triggers NAFLD characterized by a deregulation of lipid metabolism and lipophagy blockade
(Wiley, 2023)Intravascular hemolysis is a common feature of different clinical entities, including sickle cell disease and malaria. Chronic hemolytic disorders are associated with hepatic damage; however, it is unknown whether heme ... -
Splicing Machinery Is Impaired in Oral Squamous Cell Carcinomas and Linked to Key Pathophysiological Features
(MDPI, 2024)Alternative splicing dysregulation is an emerging cancer hallmark, potentially serving as a source of novel diagnostic, prognostic, or therapeutic tools. Inhibitors of the activity of the splicing machinery can exert ... -
Impact of Cognitive Impairment on Quality of Life in Multiple Sclerosis Patients—A Comprehensive Review
(MDPI, 2024)Multiple sclerosis (MS) is characterized by a variety of symptoms that have a major impact on quality of life (QoL) even in early stages. In addition to individual motor, sensory, visual disturbances, and brainstem and ... -
Preclinical Characterization of Pharmacologic NAD+Boosting as a Promising Therapeutic Approach inRheumatoid Arthritis
(Wiley, 2023)Objective: We analyzed NAD+ metabolism in patients with rheumatoid arthritis (RA), its association with disease activity and clinical outcomes of RA, and the therapeutic potential of pharmacologic NAD+ boosting. Methods: ...