Listar DBCFI-Artículos, capítulos... por autor "13936ddb-d209-42c4-8fe1-dd5a928282c5"

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    • Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer 

      Jiménez-Vacas, J.M.; Gómez Gómez, Enrique; Montero-Hidalgo, Antonio J.; Herrero-Aguayo, V.; L-López, Fernando; Sánchez-Sánchez, Rafael; Guler, Ipek; Blanca, Ana; Méndez-Vidal, María José; Carrasco, Julia; López-Miranda, José; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)
      Recent data suggested that plasma Ghrelin O-Acyl Transferase enzyme (GOAT) levels could represent a new diagnostic biomarker for prostate cancer (PCa). In this study, we aimed to explore the diagnostic and prognostic/agg ...

    • Does telotristat have a role in preventing carcinoid heart disease? 

      Herrera-Martínez, Aura D.; Fuentes-Fayos, Antonio C.; Sánchez-Sánchez, Rafael; Montero-Hidalgo, Antonio J .; Sarmento-Cabral, André; Gálvez-Moreno, M. Ángeles; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2024)
      Carcinoid heart disease (CHD) is a frequent and life-threatening complication in patients with carcinoid tumors. Its clinical management is challenging is some cases since serotonin-induced valve fibrosis leads to heart ...

    • Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Novel Potential Biomarker in Gastroenteropancreatic Neuroendocrine Tumors 

      Herrera-Martínez, Aura D.; Gahete Ortiz, Manuel D.; Sánchez-Sánchez, Rafael; Alors-Pérez, Emilia; Pedraza-Arévalo, Sergio; Serrano-Blanch, Raquel; Martínez-Fuentes, Antonio J.; Castaño, Justo P.; Luque, Raúl M.; Gálvez-Moreno, M. Ángeles (Nature.com, 2018)
      Objectives: The association between the presence and alterations of the components of the ghrelin system and the development and progression of neuroendocrine tumors (NETs) is still controversial and remains unclear. Methods: ...

    • Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer 

      Gómez-Gómez, E.; Jiménez-Vacas, J.M.; Pedraza-Arévalo, Sergio; López-López, F.; Herrero-Aguayo, V.; Hormaechea Agulla, Daniel; Valero-Rosa, J.; Ibáñez-Costa, Alejandro; León González, A.J.; Sánchez-Sánchez, Rafael; Gónzalez Serrano, T.; Requena-Tapia, M.J.; Castaño, Justo P.; Carrasco-Valiente, J.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)
      Engrailed variant-2 (EN2) has been suggested as a potential diagnostic biomarker; however, its presence and functional role in prostate cancer (PCa) cells is still controversial or unknown. Here, we analyzed 1) the ...

    • Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer 

      Sáez Martínez, Prudencio; Jiménez-Vacas, J.M.; León González, A.J.; Herrero-Aguayo, V.; Montero-Hidalgo, Antonio J.; Gómez-Gómez, E.; Sánchez-Sánchez, Rafael; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2020)
      Certain components of the somatostatin-system play relevant roles in Prostate Cancer (PCa), whose most aggressive phenotype (Castration-Resistant-PCa (CRPC)) remains lethal nowadays. However, neuronostatin and the G ...