Listar DBCFI-Artículos, capítulos... por autor "5555dd0e-560b-4e17-a5ab-a41864b9d964"
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A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study
Villasanta-González, Alejandro; Alcalá Díaz, Juan Francisco; Vals-Delgado, Cristina; Arenas, Antonio Pablo; Cardelo, Magdalena P.; Romero-Cabrera, Juan Luis; Rodríguez-Cantalejo, Fernando; Delgado-Lista, Javier; Malagón, María M.; Pérez-Martínez, Pablo; Schulze, Matthias B.; Camargo García, A.; López-Miranda, José (Springer, 2021)Purpose: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We ... -
An altered microbiota pattern precedes Type 2 diabetes mellitus development: From the CORDIOPREV study
Vals-Delgado, Cristina; Alcalá-Diaz, Juan F.; Molina-Abril, Helena; Roncero-Ramos, Irene; Caspers, Martien P.M.; Schuren, Frank H.J.; Broek, Tim J. Van den; Luque, Raúl M.; Pérez-Martínez, Pablo; Katsiki, Niki; Delgado-Lista, Javier; Ordovas, José M.; Ommene, Ben van; Camargo García, A.; López-Miranda, José (Elsevier, 2021)Introduction. A distinctive gut microbiome have been linked to type 2 diabetes mellitus (T2DM). We aimed to evaluate whether gut microbiota composition, in addition to clinical biomarkers, could improve the prediction of ... -
Association between Diet Quality and Risk of Type 2 Diabetes Mellitus in Patients with Coronary Heart Disease: Findings from the CORDIOPREV Study
Rivas García, Lorenzo; Quintana-Navarro, Gracia M.; Alcalá Díaz, Juan Francisco; Torres‑Peña, J.D.; Arenas de Larriva, Antonio P.; Rangel-Zuñiga, Oriol Alberto; López-Moreno, Alejandro; Malagón, María M.; Katsiki, Niki; Pérez Martínez, Pablo; López Miranda, José; Delgado-Lista, Javier (MDPI, 2024)The incidence of type 2 diabetes mellitus (T2DM) is growing in Western countries. Nutritional interventions that promote high-quality dietary patterns could help reverse this trend. We aimed to evaluate whether changes in ... -
Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial
Roncero-Ramos, Irene; Gutiérrez Mariscal, Francisco Miguel; Gómez Delgado, Francisco; Villasanta-González, Alejandro; Torres‑Peña, J.D.; Cruz‐Ares, Silvia de la; Rangel Zúñiga, Oriol Alberto; Luque, Raúl M.; Ordovas, José M.; Delgado-Lista, Javier; Pérez-Martínez, Pablo; Camargo García, A.; Alcalá Díaz, Juan Francisco; López-Miranda, José (Elsevier, 2021)In order to assess whether previous hepatic IR (Hepatic-IR fasting) and beta-cell functionality could modulate type 2 diabetes remission and the need for starting glucose- lowering treatment, newly-diagnosed type 2 diabetes ... -
Ceruloplasmin and Coronary Heart Disease-A Systematic Review
Arenas de Larriva, Antonio P.; Limia-Pérez, Laura; Alcalá Díaz, Juan Francisco; Alonso, Álvaro; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2020)Several studies indicate that oxidative stress might play a central role in the initiation and maintenance of cardiovascular diseases. It remains unclear whether ceruloplasmin acts as a passive marker of inflammation or ... -
Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study
Gahete Ortiz, Manuel D.; Río Moreno, Mercedes del; Carpio Camargo, Antonio José; Alcalá Díaz, Juan Francisco; Alors-Pérez, Emilia; Delgado-Lista, Javier; Reyes Pupo, Oscar Gabriel; Ventura, Sebastián; Pérez Martínez, Pablo; Castaño, Justo P.; López Miranda, José; Luque, Raúl M. (Elsevier, 2018)Background: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, ... -
Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer
Jiménez-Vacas, J.M.; Gómez Gómez, Enrique; Montero-Hidalgo, Antonio J.; Herrero-Aguayo, V.; L-López, Fernando; Sánchez-Sánchez, Rafael; Guler, Ipek; Blanca, Ana; Méndez-Vidal, María José; Carrasco, Julia; López-Miranda, José; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)Recent data suggested that plasma Ghrelin O-Acyl Transferase enzyme (GOAT) levels could represent a new diagnostic biomarker for prostate cancer (PCa). In this study, we aimed to explore the diagnostic and prognostic/agg ... -
Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases
Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Limia-Pérez, Laura; Romero-Cabrera, Juan Luis; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2020)Apart from its main function in the mitochondria as a key element in electron transport, Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant action in the generation of signals and the ... -
Dietary Intervention Modulates the Expression of Splicing Machinery in Cardiovascular Patients at High Risk of Type 2 Diabetes Development: From the CORDIOPREV Study
Río Moreno, Mercedes del; Luque, Raúl M.; Rangel Zúñiga, Oriol Alberto; Alors-Pérez, Emilia; Alcalá Díaz, Juan Francisco; Roncero-Ramos, Irene; Camargo García, A.; Gahete Ortiz, Manuel D.; López-Miranda, José; Castaño, Justo P. (MDPI, 2020)Type-2 diabetes mellitus (T2DM) has become a major health problem worldwide. T2DM risk can be reduced with healthy dietary interventions, but the precise molecular underpinnings behind this association are still incompletely ... -
Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study
Cruz‐Ares, Silvia de la; Cardelo, Magdalena P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; García-Ríos, Antonio; Katsiki, Niki; Malagón, María M.; López-Miranda, José; Pérez-Martínez, Pablo; Yubero-Serrano, Elena M. (MDPI, 2020)Endothelial dysfunction and intima-media thickness of common carotid arteries (IMT-CC) are considered subclinical markers of atherosclerotic cardiovascular disease (ASCVD). Advanced glycation end products (AGEs) are increased ... -
Evolution of Metabolic Phenotypes of Obesity in Coronary Patients after 5 Years of Dietary Intervention: From the CORDIOPREV Study
Martín-Piedra, Laura; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Romero-Cabrera, Juan Luis; Torres‑Peña, J.D.; Caballero-Villarraso, Javier; Luque, Raúl M.; Pérez-Martínez, Pablo; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2021)Background: Obesity phenotypes with different metabolic status have been described previously. We analyzed metabolic phenotypes in obese coronary patients during a 5-year follow-up, and examined the factors influencing ... -
Long-term consumption of a mediterranean diet or a low-fat diet on kidney function in coronary heart disease patients: The CORDIOPREV randomized controlled trial
Podadera-Herreros, Alicia; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; Jiménez Torres, José; Cruz Ares, Silvia de la; Arenas de Larriva, Antonio P.; Cardelo, Magdalena P.; Torrez-Peña, Juan David; Luque, Raúl M.; Ordovás, José María; Delgado-Lista, Javier; López-Miranda, José; Yubero-Serrano, Elena M. (Elsevier, 2022)Background & aims: Lifestyle and dietary habits influence kidney function, playing an important role in the prevention and development of chronic kidney disease (CKD). The effectiveness of the Mediterranean diet in preserving ... -
Modifications of plasma proteome in healthy humans fed o a coenzymen Q-10 supplemented diet
Santos-González, Mónica; Villalba, José Manuel; Pérez-Jiménez, Francisco; López-Miranda, José (Universidad de Córdoba, Servicio de Publicaciones, 2009) -
Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity
Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García-Navarro, Socorro; Gracia-Navarro, F.; Frühbeck, Gema; Vázquez Martínez, Rafael; Tinahones, Francisco J.; Malagón, María M.; López-Miranda, José (Public Libray of Science (PLOS), 2011)Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ... -
Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity
Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García Navarro, S.; Gracia-Navarro, F.; Tinahones, Francisco J.; López-Miranda, José; Frühbeck, Gema; Vázquez Martínez, Rafael; Malagón, María M. (PLOS, 2011)Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ... -
The stromal-vascular fraction of adipose tissue contributes to major differences between subcutaneous and visceral fat depots
Peinado, Juan R.; Jiménez Gómez, Yolanda; Pulido, Marina R.; Ortega-Bellido, María; Díaz-López, César; Padillo, Francisco; López Miranda, José; Vazquez-Martínez, Rafael; Malagón, María M. (Wiley, 2010)Adipose tissue represents a complex tissue both in terms of its cellular composition, as it includes mature adipocytes and the various cell types comprising the stromal-vascular fraction (SVF), and in relation to the ...