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Proteomic profiling of adipose tissue from Zmpste24(-/-) Mice, a model of Lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing
Peinado, Juan R.; Moral Quirós, Pedro; Pulido, Marina R.; Mariño García, Guillermo; Martínez-Chantar, M.L.; Vázquez Martínez, Rafael; Pérez Freije, José María; López Ontín, Carlos; Malagón, María M. (Science Direct, 2011)Lipodystrophy is a major disease involving severe alterations of adipose tissue distribution and metabolism. Mutations in genes encoding the nuclear envelope protein lamin A or its processing enzyme, the metalloproteinase ...