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Beta cell functionality and hepatic insulin resistance are major contributors to type 2 diabetes remission and starting pharmacological therapy: from CORDIOPREV randomized controlled trial
Roncero-Ramos, Irene; Gutiérrez Mariscal, Francisco Miguel; Gómez Delgado, Francisco; Villasanta-González, Alejandro; Torres‑Peña, J.D.; Cruz‐Ares, Silvia de la; Rangel Zúñiga, Oriol Alberto; Luque, Raúl M.; Ordovas, José M.; Delgado-Lista, Javier; Pérez-Martínez, Pablo; Camargo García, A.; Alcalá Díaz, Juan Francisco; López-Miranda, José (Elsevier, 2021)In order to assess whether previous hepatic IR (Hepatic-IR fasting) and beta-cell functionality could modulate type 2 diabetes remission and the need for starting glucose- lowering treatment, newly-diagnosed type 2 diabetes ... -
Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases
Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Limia-Pérez, Laura; Romero-Cabrera, Juan Luis; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2020)Apart from its main function in the mitochondria as a key element in electron transport, Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant action in the generation of signals and the ... -
Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study
Cruz‐Ares, Silvia de la; Cardelo, Magdalena P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; García-Ríos, Antonio; Katsiki, Niki; Malagón, María M.; López-Miranda, José; Pérez-Martínez, Pablo; Yubero-Serrano, Elena M. (MDPI, 2020)Endothelial dysfunction and intima-media thickness of common carotid arteries (IMT-CC) are considered subclinical markers of atherosclerotic cardiovascular disease (ASCVD). Advanced glycation end products (AGEs) are increased ... -
Evolution of Metabolic Phenotypes of Obesity in Coronary Patients after 5 Years of Dietary Intervention: From the CORDIOPREV Study
Martín-Piedra, Laura; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Romero-Cabrera, Juan Luis; Torres‑Peña, J.D.; Caballero-Villarraso, Javier; Luque, Raúl M.; Pérez-Martínez, Pablo; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2021)Background: Obesity phenotypes with different metabolic status have been described previously. We analyzed metabolic phenotypes in obese coronary patients during a 5-year follow-up, and examined the factors influencing ... -
Long-term consumption of a mediterranean diet or a low-fat diet on kidney function in coronary heart disease patients: The CORDIOPREV randomized controlled trial
Podadera-Herreros, Alicia; Alcalá Díaz, Juan Francisco; Gutiérrez Mariscal, Francisco Miguel; Jiménez Torres, José; Cruz Ares, Silvia de la; Arenas de Larriva, Antonio P.; Cardelo, Magdalena P.; Torrez-Peña, Juan David; Luque, Raúl M.; Ordovás, José María; Delgado-Lista, Javier; López-Miranda, José; Yubero-Serrano, Elena M. (Elsevier, 2022)Background & aims: Lifestyle and dietary habits influence kidney function, playing an important role in the prevention and development of chronic kidney disease (CKD). The effectiveness of the Mediterranean diet in preserving ...