• LRP10, PGK1 and RPLP0: best reference genes in periprostatic adipose tissue under obesity and prostate cancer conditions 

      Pérez Gómez, J.M.; Porcel-Pastrana, Francisco; luz borrero, Marina De La; Montero-Hidalgo, Antonio J.; Gómez-Gómez, E.; Herrera-Martínez, Aura D.; Guzmán-Ruiz, Rocío; Malagón, María M.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2023)
      Obesity (OB) is a metabolic disorder characterized by adipose tissue dysfunction that has emerged as a health problem of epidemic proportions in recent decades. OB is associated with multiple comorbidities, including some ...
    • Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer 

      Gómez-Gómez, E.; Jiménez-Vacas, J.M.; Pedraza-Arévalo, Sergio; López-López, F.; Herrero-Aguayo, V.; Hormaechea Agulla, Daniel; Valero-Rosa, J.; Ibáñez-Costa, Alejandro; León González, A.J.; Sánchez-Sánchez, Rafael; Gónzalez Serrano, T.; Requena-Tapia, M.J.; Castaño, Justo P.; Carrasco-Valiente, J.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)
      Engrailed variant-2 (EN2) has been suggested as a potential diagnostic biomarker; however, its presence and functional role in prostate cancer (PCa) cells is still controversial or unknown. Here, we analyzed 1) the ...
    • Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer 

      Sáez Martínez, Prudencio; Jiménez-Vacas, J.M.; León González, A.J.; Herrero-Aguayo, V.; Montero-Hidalgo, Antonio J.; Gómez-Gómez, E.; Sánchez-Sánchez, Rafael; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2020)
      Certain components of the somatostatin-system play relevant roles in Prostate Cancer (PCa), whose most aggressive phenotype (Castration-Resistant-PCa (CRPC)) remains lethal nowadays. However, neuronostatin and the G ...