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Vitamin d deficiency with high parathyroid hormone levels is related to late onset SEPSIS among preterm infants
dc.contributor.author | Tofe‑Valera, I. | |
dc.contributor.author | Pérez Navero, Juan Luis | |
dc.contributor.author | Caballero‑Villarras, J. | |
dc.contributor.author | Cañete, M. D. | |
dc.contributor.author | Villa Jiménez, Rosalía | |
dc.contributor.author | Torre‑Aguilar, M. J. de la | |
dc.date.accessioned | 2024-02-12T09:54:22Z | |
dc.date.available | 2024-02-12T09:54:22Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | http://hdl.handle.net/10396/27414 | |
dc.description.abstract | Summary Preterm infants (PTs) are at greater risk for vitamin D defciency, which relates to the possibility of a higher incidence of comorbidities. Our goal was twofold, 1) to monitor vitamin D, calcium, phosphorus, parathyroid hormone (PTH), matrix metalloproteinase-8 (MMP-8) serum levels at three-time points during hospitalization, and 2) to assess the association between 25-hydroxyvitamin D (25OHD) levels and outcomes in PTs. Methods We carried out a follow-up on 50 Caucasian PTs≤32weeks of gestational age (GA) and/or≤1500g birth weight at 28days and at 4months. PTs were divided into two subgroups for tests of association with clinical outcomes based on vitamin D defcient infants 25(OH) D cord blood levels: ≤ 20ng/ml). At an initial stage, 25(OH) D levels were determined in maternal/preterm blood samples and were compared to full term delivery infants. Results There were no diferences in 25(OH) D serum levels at birth when comparing PTs to term infants, or regard ing maternal levels. A strong positive correlation was detected between maternal and neonatal 25(OH) D serum levels among PTs and term infants (r: 0.466; p60pg/mL; group 2: vitamin D>20 and PTH | es_ES |
dc.format.mimetype | application/pdf | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | BMC | es_ES |
dc.rights | https://creativecommons.org/licenses/by/4.0/ | es_ES |
dc.source | Tofe-Valera, I., Pérez-Navero, J.L., Caballero-Villarraso, J. et al. Vitamin d deficiency with high parathyroid hormone levels is related to late onset SEPSIS among preterm infants. BMC Pregnancy Childbirth 23, 23 (2023). https://doi.org/10.1186/s12884-022-05334-2 | es_ES |
dc.subject | 25(OH) D levels | es_ES |
dc.subject | Vitamin D defciency | es_ES |
dc.subject | Preterm infants | es_ES |
dc.subject | Low birth weight | es_ES |
dc.subject | Sepsis | es_ES |
dc.subject | Parathyroid hormone | es_ES |
dc.title | Vitamin d deficiency with high parathyroid hormone levels is related to late onset SEPSIS among preterm infants | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.relation.publisherversion | https://doi.org/10.1186/s12884-022-05334-2 | es_ES |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es_ES |