ListarDepartamento de Anatomía y Anatomía Patológica Comparadas y Toxicología por tema "Fasciola hepatica"
Mostrando ítems 1-20 de 25
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A Partially Protective Vaccine for Fasciola hepatica Induced Degeneration of Adult Flukes Associated to a Severe Granulomatous Reaction in Sheep
(MDPI, 2021)Fasciolosis is an important economic disease of livestock. There is a global interest in the development of protective vaccines since current anthelmintic therapy is no longer sustainable. A better knowledge of the ... -
Apoptosis of peritoneal leucocytes during early stages of Fasciola hepatica infections in sheep
(Elsevier, 2017)Several immunomodulatory properties have been described in Fasciola hepatica infections. Apoptosis has been shown to be an effective mechanism to avoid the immune response in helminth infections. The aim of the present ... -
Cambios celulares y moleculares en el perioteneo asociados con la patología hepática en fases tempranas de la infección con fasciola hepática en ovejas
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016) -
Caracterización de macrófagos peritoneales de ovejas en fases tempranas de infección experimental con fasciola hepática
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016) -
Characterization of dendritic cells and follicular dendritic cells in the hepatic lymph nodes and liver of sheep experimentally infected with Fasciola hepatica
(Springer, 2020)Fasciola hepatica has been shown to have a high capacity for immunomodulation of the host response, making the development of protective vaccines extremely difficult. One of these immunomodulation mechanisms is the impairment ... -
Comparative dynamics of peritoneal cell immunophenotypes in sheep during the early and late stages of the infection with Fasciola hepatica by flow cytometric analysis
(Springer, 2018)Background: The peritoneal cell populations (PCP) are thought to play a crucial role during the early immune response in Fasciola hepatica infection while newly excysted juveniles (NEJ) are migrating in the peritoneal ... -
Distribución de linfocitos FOXP3 reguladores en hígado y nódulos linfáticos de ovejas y cabras infectadas con fasciola hepática
(Universidad de Córdoba. Departamento de Anatomía y Anatomía Patológica Comparadas, 2016) -
Distribution of Foxp3+ T cells in the liver and hepatic lymph nodes of goats and sheep experimentally infected with Fasciola hepatica
(Elsevier, 2016)Foxp3 regulatory T cells (Tregs) are now considered to play a key role in modulation of immune responses during parasitic helminth infections. Immunomodulation is a key factor in Fasciola hepatica infection; however, the ... -
Estudio del hígado y líquido peritoneal en fases tempranas de ovejas infectadas experimentalmente con Fasciola hepatica
(Universidad de Córdoba, UCOPress, 2018)La fasciolosis causada por Fasciola hepatica es una enfermedad parasitaria de gran repercusión sanitaria y económica en rumiantes, principalmente en zonas de clima templado. Este parásito ha desarrollado mecanismos ... -
Estudios de los mecanismos de inmunomodulación por Fasciola hepática: Apoptosis y linfocitos T reguladores
(Universidad de Córdoba, UCOPress, 2017)La fasciolosis causada por Fasciola hepatica es una enfermedad económicamente muy importante en rumiantes en climas templados. F. hepatica ha desarrollado una amplia variedad de mecanismos para munomodular o suprimir la ... -
Evaluación de lesiones hepáticas y respuesta inmunitaria local en ovejas vacunadas con CL1 e infectadas con Fasciola hepatica
(Universidad de Córdoba, UCOPress, 2018)El objetivo del presente estudio, ha sido, por un lado evaluar la respuesta inmunitaria en hígado y nódulos linfáticos hepáticos (NLH) de ovejas no vacunada y vacunadas Catepsina L1 recombinante (rCL1) e infectadas con ... -
Evaluación del daño hepático y respuesta inmunitaria local en cabras vacunadas con Catepsina L1 e infectadas con Fasciola Hepatica
(Universidad de Córdoba, UCOPress, 2016)El objetivo del presente estudio ha sido estudiar la eficacia protectora, así como las lesiones hepáticas y la respuesta inmunitaria inmunitaria local en cabras inmunizadas con catepsina L1 recombinante (CL1) de F. ... -
Evaluation of Reproductive Histology Response of Adult Fasciola hepatica in Goats Vaccinated with Cathepsin L Phage-Exposed Mimotopes
(MDPI, 2024)Fasciolosis, a globally re-emerging zoonotic disease, is mostly caused by the parasitic infection with Fasciola hepatica, often known as the liver fluke. This disease has a considerable impact on livestock productivity. ... -
Evaluation of Th1/Th2, regulatory cytokines and transcriptional factor FoxP3 in sheep immunized with a partially protective and non-protective vaccine and challenged with Fasciola hepatica
(BMC (Springer), 2024)Gene expression for Th1/Th2 cytokines (IL-4 and IFN-ɣ), regulatory cytokines (TGF-β and IL-10) and the transcriptional factor FoxP3 was analyzed in the liver and hepatic lymph nodes (HLN) from sheep immunized with partially ... -
Expression of free radicals by peritoneal cells of sheep during the early stages of Fasciola hepatica infection
(Springer, 2018)Background: The majority of vaccination studies against infection with F. hepatica in a natural host have been conducted at the late stage of the infection when the host's immune response is already immunomodulated by the ... -
Fasciola hepatica induces eosinophil apoptosis in the migratory and biliary stages of infection in sheep
(Elsevier, 2016)The aim of the present work was to evaluate the number of apoptotic eosinophils in the livers of sheep experimentally infected with Fasciola hepatica during the migratory and biliary stages of infection. Four groups (n = ... -
Fasciola hepatica induces Foxp3 T cell, proinflammatory and regulatory cytokine overexpression in liver from infected sheep during early stages of infection
(Springer, 2018)The expression of T regulatory cells (Foxp3), regulatory (interleukin [IL]-10 and transforming growth factor beta [TGF-β]) and proinflammatory (tumor necrosis factor alpha [TNF-α] and interleukin [IL]-1β) cytokines was ... -
Fasciola hepatica primoinfections and reinfections in sheep drive distinct Th1/Th2/Treg immune responses in liver and hepatic lymph node at early and late stages
(Springer, 2023)The expression of proinflammatory (IL-1β, IFN-γ, TNF-α) and regulatory (IL-10, TGF-β, IL-4) cytokines, as well as the transcription factor FoxP3, was quantified in the liver and hepatic lymph node (HLN) of sheep primoinfected ... -
Fasciolosis: pathogenesis, host-parasite interactions, and implication in vaccine development
(Frontiers, 2023)Fasciola hepatica has a worldwide distribution causing important economic losses in animal production industry. Human fasciolosis is considered an emerging zoonosis in areas of Andean America, Asia, and Africa. The control ...