Listar Departamento de Biología Celular, Fisiología e Inmunología por autor "12bd7fe9-d85f-4545-8315-40d8ba1cb5b6"
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Preclinical Characterization of Pharmacologic NAD+Boosting as a Promising Therapeutic Approach inRheumatoid Arthritis
Pérez Sánchez, Carlos; Escudero Contreras, Alejandro; Cerdó, Tomás; Sánchez-Mendoza, Luz Marina; Llamas Urbano, Adrián; Arias de la Rosa, Iván; Pérez Rodríguez, Miguel; Muñoz-Barrera, Laura; Ábalos-Aguilera, María del Carmen; Barbarroja, Nuria; Calvo Gutiérrez, Jerusalém; Ortega Castro, María Rafaela; Ruiz-Vilchez, Desirée; Moreno, Juan Antonio; Burón, Isabel; González Reyes, José Antonio; López-Pedrera, Ch.; Villalba, José Manuel (Wiley, 2023)Objective: We analyzed NAD+ metabolism in patients with rheumatoid arthritis (RA), its association with disease activity and clinical outcomes of RA, and the therapeutic potential of pharmacologic NAD+ boosting. Methods: ... -
Therapeutic Potential and Immunomodulatory Role of Coenzyme Q10 and Its Analogues in Systemic Autoimmune Diseases
López-Pedrera, Ch.; Villalba, José Manuel; Patiño-Trives, Alejandra Mª; Luque-Tévar, María; Barbarroja, Nuria; Aguirre, M.A.; Escudero Contreras, Alejandro; Pérez Sánchez, Carlos (MDPI, 2021)Coenzyme Q10 (CoQ10) is a mitochondrial electron carrier and a powerful lipophilic antioxidant located in membranes and plasma lipoproteins. CoQ10 is endogenously synthesized and obtained from the diet, which has raised ...