Listar Departamento de Biología Celular, Fisiología e Inmunología por título
Mostrando ítems 1-20 de 289
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3-Phenylcoumarins as Inhibitors of HIV-1 Replication
(MDPI, 2012)We have synthesized fourteen 3-phenylcoumarin derivatives and evaluated their anti-HIV activity. Antiviral activity was assessed on MT-2 cells infected with viral clones carrying the luciferase gene as reporter. Inhibition ... -
5—hidroxitriptamina en encéfalo total y en diversas regiones del sistema nervioso central de ratas intoxicadas con el extracto acuoso de Astragalus lusitanicus Lam
(Universidad de Córdoba, Servicio de Publicaciones, 1986)The administration of the aqueous extract of Astragalus lusitanicus to rats, in a dose" corresponding to 45 g wet plant/kg body weight, brougW about the sintomatology of a central nervous system depression that persisted ... -
A genome-wide association study of mare fertility in the Pura Raza Español horse
(Elsevier, 2022)Despite the economic importance of fertility for the horse industry, few efforts have been made to achieve a better understanding of the genetic mechanisms underlying its control. This is probably due to the difficulty of ... -
A Meta-Analytic Approach to Predict Methane Emissions from Dairy Goats Using Milk Fatty Acid Profile
(MDPI, 2020)The aim of this work was to develop an equation to predict methane yield (CH4, g/kg dry matter intake) from dairy goats using milk fatty acid (FA) profile. Data from 12 research papers (30 treatments and 223 individual ... -
A Novel Human Ghrelin Variant (In1-Ghrelin) and Ghrelin-O-Acyltransferase Are Overexpressed in Breast Cancer: Potential Pathophysiological Relevance
(Public Library Of Science (PLOS), 2011)The human ghrelin gene, which encodes the ghrelin and obestatin peptides, contains 5 exons (Ex), with Ex1-Ex4 encoding a 117 amino-acid (aa) preproprotein that is known to be processed to yield a 28-aa (ghrelin) and/or a ... -
A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study
(Springer, 2021)Purpose: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We ... -
A Straightforward Cytometry-Based Protocol for the Comprehensive Analysis of the Inflammatory Valve Infiltrate in Aortic Stenosis
(MDPI, 2023)Aortic stenosis (AS) is a frequent cardiac disease in old individuals, characterized by valvular calcification, fibrosis, and inflammation. Recent studies suggest that AS is an active inflammatory atherosclerotic-like ... -
Acciones tuteladas para la formación de profesorado novel: diseño e implementación de actividades y recursos de aprendizaje en soporte LMS
(UCOPress, 2018)El presente artículo describe el desarrollo de un Proyecto formativo para la implementación de actividades y recursos de aprendizaje en la plataforma UCO-Moodle por parte de profesorado novel, bajo tutela y coordinación ... -
Activation of microglia in specific hypothalamic nuclei and the cerebellum of adult rats exposed to neonatal overnutrition
(Blackwell Publishing, 2011)Much attention has been drawn to the possible involvement of hypothalamic inflammation in the pathogenesis of metabolic disorders, especially in response to a high-fat diet. Microglia, the macrophages of the central nervous ... -
Aislamiento in situ de núcleos de células HeLa
(Universidad de Córdoba, Servicio de Publicaciones, 1978)By optical microscope with phase contrast we have studied the modifications of nuclei from HeLa cells isolated in situ by means of Triton X-100. We remark the structure continuance until 60 days after isolation: The method ... -
Alteración del crecimiento celular por la inhibición de quinona reductasas
(Universidad de Córdoba, Servicio de Publicaciones, 2011)La familia de las quinona reductasas agrupa un conjunto de enzimas caracterizadas por la reducción de sustratos quinónicos a semiquinonas e hidroquinonas usando NAD(P)H como donador de electrones. El interés creciente por ... -
Alterations in growth and cell death by genetic deletion of the antioxidan response factor Nrf2 ist target, the quinone reductase NQ01
(Universidad de Córdoba, UCOPress, 2015)To neutralize oxidative stress insults, cells have acquire complex defense mechanisms which are induced in a highly coordinated way. This coordinated response is regulated through a cis-regulatory element, called the ... -
An altered microbiota pattern precedes Type 2 diabetes mellitus development: From the CORDIOPREV study
(Elsevier, 2021)Introduction. A distinctive gut microbiome have been linked to type 2 diabetes mellitus (T2DM). We aimed to evaluate whether gut microbiota composition, in addition to clinical biomarkers, could improve the prediction of ... -
Analysis of the roles of kisspeptins and the tachykinin receptor, Tacr2, in the control of Reproduction: novel interactive pathways, regulatory mechanisms and metabolic implications
(Universidad de Córdoba, UCOPress, 2021)For sake of clarity, this Doctoral Thesis has been divided in 3 main experimental sets: In the Experimental Set 1, a comprehensive series of phenotypical, pharmacological, behavioral and histological analyses were conducted ... -
Analysis of the roles of neuropeptidergic system and micrornas in the control of puberty
(Universidad de Córdoba, Servicio de Publicaciones, 2015)La pubertad es la culminación de una cascada de eventos del desarrollo que conduce a la activación del eje hipotálamo-hipófiso-gonadal (HHG) y la adquisición de la capacidad reproductora . Dicha activación es desencadenada ... -
Anatomía del craneoencéfalo del ovino (raza merina) y sus fundamentos topográficos para una estereotaxis aplicada
(Universidad de Córdoba, Servicio de Publicaciones, 1983)Ten heads of ovins (Merino race) are put to radiologic observation before and after repletions controlled by means of contrast in theeric e phalic cavities, resulting essencial for the images which are obtained, the perfect ... -
Análisis de los sistemas RFRP/NPFF1R y Kiss1/Gpr54 en la regulación de la función reproductora y de la homeostasis metabólica
(Universidad de Córdoba, Servicio de Publicaciones, 2014)En las sociedades desarrolladas existe un especial interés en la manipulación de la capacidad reproductora, ya sea para su supresión/inhibición temporal, para su restauración en condiciones de infertilidad, o para el ... -
Análisis del papel del sistema Kiss1/Kisspeptinas en el control de la función metabólica: estudios farmacológicos y de genómica funcional
(Universidad de Córdoba, UCOPress, 2019)Esta Tesis Doctoral se ha dividido en tres bloques experimentales principales. En el bloque experimental 1, se ha evaluado las respuestas de parámetros metabólicos básicos a la administración central o periférica de Kp- ... -
Antagonists of Growth Hormone-Releasing Hormone Inhibit the Growth of Pituitary Adenoma Cells by Hampering Oncogenic Pathways and Promoting Apoptotic Signaling
(MDPI, 2021)Pituitary adenomas (PAs) are intracranial tumors, often associated with excessive hormonal secretion and severe comorbidities. Some patients are resistant to medical therapies; therefore, novel treatment options are needed. ...