• Non-Coding RNAs in Kidney Diseases: The Long and Short of Them 

      Moreno, Juan Antonio; Hamza, Eya; Guerrero-Hue, Melania; Rayego-Mateos, Sandra; García-Caballero, Cristina; Vallejo-Mudarra, Mercedes; Metzinger, Laurent; Metzinger-Le Meuth, Valérie (MDPI, 2021)
      Recent progress in genomic research has highlighted the genome to be much more transcribed than expected. The formerly so-called junk DNA encodes a miscellaneous group of largely unknown RNA transcripts, which contain the ...
    • Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy 

      Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; Guerrero-Hue, Melania; García-Caballero, Cristina; Vázquez-Carballo, Cristina; Mas, Sebastián; Sanz, Ana Belén; Herencia, Carmen; Mezzano, Sergio; Gómez-Guerrero, Carmen; Moreno, Juan Antonio; Egido, Jesús (MDPI, 2020)
      Diabetic nephropathy (DN) is associated with an increased morbidity and mortality, resulting in elevated cost for public health systems. DN is the main cause of chronic kidney disease (CKD) and its incidence increases the ...
    • Protective Role of Nrf2 in Renal Disease 

      Guerrero-Hue, Melania; Rayego-Mateos, Sandra; Vázquez-Carballo, Cristina; Palomino-Antolín, Alejandra; García-Caballero, Cristina; Opazo-Ríos, Lucas; Morgado-Pascual, José Luis; Herencia, Carmen; Mas, Sebastián; Ortiz, Alberto; Rubio-Navarro, Alfonso; Egea, Javier; Villalba, José Manuel; Egido, J.; Moreno, Juan Antonio (MDPI, 2020)
      Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ...
    • Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury 

      Vázquez-Carballo, Cristina; Herencia, Carmen; Guerrero-Hue, Melania; García-Caballero, Cristina; Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; González-Guerrero, Cristian; Vallejo-Mudarra, Mercedes; Cortegano, Isabel; Gaspar, María Luisa; Andrés, Belén de; Egido, J.; Moreno, Juan Antonio (Wiley, 2022)
      Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, ...
    • Toll-Like Receptors in Acute Kidney Injury 

      Vázquez-Carballo, Cristina; Guerrero-Hue, Melania; García-Caballero, Cristina; Rayego-Mateos, Sandra; Opazo-Ríos, Lucas; Morgado-Pascual, José Luis; Herencia, Carmen; Vallejo-Mudarra, Mercedes; Cortegano, Isabel; Gaspar, María Luisa; Andrés, Belén de; Egido, Jesús; Moreno, Juan Antonio (MDPI, 2021)
      Acute kidney injury (AKI) is an important health problem, affecting 13.3 million individuals/year. It is associated with increased mortality, mainly in low- and middle-income countries, where renal replacement therapy is ...