Listar Departamento de Biología Celular, Fisiología e Inmunología por autor "fc98ec0f-7fea-4873-841e-12f58ca43efe"

Mostrando ítems 21-25 de 25

    • The ghrelin O-acyltransferase–ghrelin system reduces TNF-α-induced apoptosis and autophagy in human visceral adipocytes 

      Rodríguez, A; Gómez-Ambrosi, Javier; Catalán, Victoria; Rotellar, Fernando; Valentí, Víctor; Silva, Camilo; Mugueta, C.; Pulido, Marina R.; Vázquez, R.; Salvador, Javier; Malagón, María M.; Colina, I.; Frühbeck, Gema (SpringerLink, 2012)
      Aims/hypothesis Proinflammatory and proapoptotic cytokines such as TNF-α are upregulated in human obesity. We evaluated the association between ghrelin isoforms (acylated and desacyl ghrelin) and TNF-α in obesity and ...

    • The l-α-Lysophosphatidylinositol/GPR55 system and its potential role in human obesity 

      Moreno-Navarrete, José María; Catalán, Victoria; Whyte, Lauren; Díaz-Arteaga, Adenis; Vázquez-Martínez, Rafael; Rotellar, Fernando; Guzmán-Ruiz, Rocío; Gómez-Ambrosi, Javier; Pulido, Marina R.; Russell, Wendy R.; Imbernón, Mónica; Ross, Ruth A.; Malagón, María M.; Diéguez, Carlos; Fernández-Real, José Manuel; Frühbeck, Gema; Nogueiras, Rubén (American Diabetes Asociation, 2012)
      GPR55 is a putative cannabinoid receptor, and l-α-lysophosphatidylinositol (LPI) is its only known endogenous ligand. We investigated 1) whether GPR55 is expressed in fat and liver; 2) the correlation of both GPR55 and LPI ...

    • The potential role of the adipokine HMGB1 in obesity and insulin resistance. Novel effects on adipose tissue biology 

      Guzmán Ruiz, R.; Tercero-Alcázar, C.; López-Alcalá, J.; Sánchez Ceinos, Julia; Malagón, María M.; Gordon, Ana (Elsevier, 2021)
      Discovery of the adipose tissue as a major source of signaling molecules almost three decades ago set a novel physiological paradigm that paved the way for the identification of metabolic organs as endocrine organs. ...

    • The Role of Autophagy in White Adipose Tissue Function: Implications for Metabolic Health 

      Clemente-Postigo, Mercedes; Tinahones, Alberto; Bekay, Rajaa El; Malagón, María M.; Tinahones, Francisco J. (MDPI, 2020)
      White adipose tissue (WAT) is a highly adaptive endocrine organ that continuously remodels in response to nutritional cues. WAT expands to store excess energy by increasing adipocyte number and/or size. Failure in WAT ...

    • The stromal-vascular fraction of adipose tissue contributes to major differences between subcutaneous and visceral fat depots 

      Peinado, Juan R.; Jiménez Gómez, Yolanda; Pulido, Marina R.; Ortega-Bellido, María; Díaz-López, César; Padillo, Francisco; López Miranda, José; Vazquez-Martínez, Rafael; Malagón, María M. (Wiley, 2010)
      Adipose tissue represents a complex tissue both in terms of its cellular composition, as it includes mature adipocytes and the various cell types comprising the stromal-vascular fraction (SVF), and in relation to the ...