Listar Departamento de Biología Celular, Fisiología e Inmunología por autor "fc98ec0f-7fea-4873-841e-12f58ca43efe"

Mostrando ítems 1-20 de 25

    • A plasma fatty acid profile associated to type 2 diabetes development: from the CORDIOPREV study 

      Villasanta-González, Alejandro; Alcalá Díaz, Juan Francisco; Vals-Delgado, Cristina; Arenas, Antonio Pablo; Cardelo, Magdalena P.; Romero-Cabrera, Juan Luis; Rodríguez-Cantalejo, Fernando; Delgado-Lista, Javier; Malagón, María M.; Pérez-Martínez, Pablo; Schulze, Matthias B.; Camargo García, A.; López-Miranda, José (Springer, 2021)
      Purpose: The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. For this reason, it is essential to identify biomarkers for the early detection of T2DM risk and/or for a better prognosis of T2DM. We ...

    • Aquaporin-11 Contributes to TGF-β1-Induced Endoplasmic Reticulum Stress in Human Visceral Adipocytes: Role in Obesity-Associated Inflammation 

      Frühbeck, Gema; Balaguer, Inmaculada; Méndez-Giménez, Leire; Valentí, Víctor; Becerril, Sara; Catalán, Victoria; Gómez-Ambrosi, Javier; Silva, Camilo; Salvador, Javier; Calamita, Giuseppe; Malagón, María M.; Rodríguez, Amaia (MDPI, 2020)
      Aquaporin-11 (AQP11) is expressed in human adipocytes, but its functional role remains unknown. Since AQP11 is an endoplasmic reticulum (ER)-resident protein that transports water, glycerol, and hydrogen peroxide (H2O2), ...

    • Association between Diet Quality and Risk of Type 2 Diabetes Mellitus in Patients with Coronary Heart Disease: Findings from the CORDIOPREV Study 

      Rivas García, Lorenzo; Quintana-Navarro, Gracia M.; Alcalá Díaz, Juan Francisco; Torres‑Peña, J.D.; Arenas de Larriva, Antonio P.; Rangel-Zuñiga, Oriol Alberto; López-Moreno, Alejandro; Malagón, María M.; Katsiki, Niki; Pérez Martínez, Pablo; López Miranda, José; Delgado-Lista, Javier (MDPI, 2024)
      The incidence of type 2 diabetes mellitus (T2DM) is growing in Western countries. Nutritional interventions that promote high-quality dietary patterns could help reverse this trend. We aimed to evaluate whether changes in ...

    • Crohn’s Disease Increases the Mesothelial Properties of Adipocyte Progenitors in the Creeping Fat 

      Madeira, Ana; Serena, Carolina; Ejarque, Miriam; Maymó-Masip, Elsa; Millán, Mónica; Navarro-Ruiz, Carmen; Guzmán Ruiz, R.; Malagón, María M.; Espin, Eloy; Martí, Marc; Menacho, Margarita; Megía, Ana; Vendrell, Joan; Fernández-Veledo, Sonia (MDPI, 2021)
      Our understanding of the interplay between human adipose tissue and the immune system is limited. The mesothelium, an immunologically active structure, emerged as a source of visceral adipose tissue. After investigating ...

    • Desarrollo de un modelo docente adaptado a los criterios metodológicos 

      Ruiz, Antonio; Gaytán, Francisco; Lucena, Concepción; Villalba, José Manuel; Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Gracia-Navarro, F.; González Reyes, José Antonio; García-Navarro, Socorro; Castaño, Justo P.; Alcaín Tejada, F.J.; Burón, Isabel; Malagón, María M. (Consejo Social de la Universidad de Córdoba, 2008)

    • Endocrinología celular y molecular 

      García Navarro, S.; Ruiz Navarro, A.; Martínez Fuentes, A.J.; Vázquez Martínez, Rafael; Durán Prado, M.; Rodríguez Pacheco, F.; Molina Sánchez, M.; Cruz García, D.; Gutiérrez Pascual, E.; Díaz-Ruiz Ruiz, A.; Gahete Ortiz, Manuel D.; Pulido Toledano, M.; Castaño, Justo P.; Malagón, María M. (Universidad de Córdoba, 2009)
      El correcto funcionamiento y homeostasis del organismo requieren un control de la secreción hormonal, cuyos defectos producen graves desórdenes endocrinos y metabólicos. Esta regulación mediada por la interacción ...

    • Endothelial Dysfunction and Advanced Glycation End Products in Patients with Newly Diagnosed Versus Established Diabetes: From the CORDIOPREV Study 

      Cruz‐Ares, Silvia de la; Cardelo, Magdalena P.; Gutiérrez Mariscal, Francisco Miguel; Torres‑Peña, J.D.; García-Ríos, Antonio; Katsiki, Niki; Malagón, María M.; López-Miranda, José; Pérez-Martínez, Pablo; Yubero-Serrano, Elena M. (MDPI, 2020)
      Endothelial dysfunction and intima-media thickness of common carotid arteries (IMT-CC) are considered subclinical markers of atherosclerotic cardiovascular disease (ASCVD). Advanced glycation end products (AGEs) are increased ...

    • Experiencias en flipped learning 

      Burón, Isabel; Avendaño, S.; Cantarero, Irene; Gahete Ortiz, Manuel D.; Guzmán Ruiz, R.; Vázquez, M.J.; Luque, Rafael; Malagón, María M.; Villalba, José Manuel; Calzado Canale, Marco Antonio (UCOPress, 2018)
      El presente trabajo describe unas experiencias de innovación docente, de igual perfil y metodología, desarrolladas por un conjunto de profesores noveles participantes bajo la tutela experta de profesorado senior. El tipo ...

    • Identification of novel genes involved in the plasticity of pituitary melanotropes in amphibians 

      Malagón, María M.; Cruz García, D.; Díaz-Ruiz Ruiz, A.; Peinado, Juan R.; Pulido, Marina R.; Araújo, J.; García Navarro, S.; Gracia-Navarro, F.; Castaño, Justo P.; Vázquez Martínez, Rafael (New York Academy os Sciences, 2009)
      Melanotrope cells from the amphibian intermediate lobe are composed of two subpopulations that exhibit opposite secretory behavior: hypersecretory and hormone-storage hyposecretory melanotropes. Isolation of these ...

    • Journal article resistin regulates pituitary somatotrope cell function through the activation of multiple signaling pathways 

      Rodríguez Pacheco, F.; Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Pulido, Marina R.; Gahete Ortiz, Manuel D.; Vaudry, Hubert; Gracia-Navarro, F.; Diéguez, Carlos; Castaño, Justo P.; Malagón, María M. (Endocrine Society, 2009)
      The adipokine resistin is an insulin-antagonizing factor that also plays a regulatory role in inflammation, immunity, food intake, and gonadal function. Although adipose tissue is the primary source of resistin, it is also ...

    • Leading Factors for Weight Gain during COVID-19 Lockdown in a Spanish Population: A Cross-Sectional Study 

      Sánchez, Enric; Lecube, Albert; Bellido, Diego; Monereo, Susana; Malagón, María M.; Tinahones, Francisco J.; Spanish Society for the Study of Obesity (MDPI, 2021)
      The increase in sedentary behaviors during the COVID-19-induced lockdown may have led to a significant weight gain. To investigate this hypothesis, a representative sample of the Spanish adult population comprising 1000 ...

    • LRP10, PGK1 and RPLP0: best reference genes in periprostatic adipose tissue under obesity and prostate cancer conditions 

      Pérez Gómez, J.M.; Porcel-Pastrana, Francisco; luz borrero, Marina De La; Montero-Hidalgo, Antonio J.; Gómez-Gómez, E.; Herrera-Martínez, Aura D.; Guzmán-Ruiz, Rocío; Malagón, María M.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2023)
      Obesity (OB) is a metabolic disorder characterized by adipose tissue dysfunction that has emerged as a health problem of epidemic proportions in recent decades. OB is associated with multiple comorbidities, including some ...

    • Melanotrope Secretory Cycle is Regulated by Physiological Inputs via the Hypothalamus 

      Vázquez Martínez, Rafael; Castaño, Justo P.; Tonon, Marie Christine; Vaudry, Hubert; Gracia-Navarro, F.; Malagón, María M. (2017-03-17)
      Previously, it has been shown that background color conditions regulate the overall activity of the frog intermediate lobe by varying the proportions of the two subtypes of melanotropes existing in the gland, the highly ...

    • Nutritional, hormonal, and depot-dependent regulation of the expression of the small GTPase Rab18 in rodent adipose tissue 

      Pulido, Marina R.; Rabanal Ruiz, Yoana; Almabouada, Farid; Díaz-Ruiz, Alberto; Burrel, María A; Vázquez, María J.; Castaño, Justo P.; Kineman, Rhonda D.; Luque, Raúl M.; Diéguez, Carlos; Vázquez-Martínez, Rafael; Malagón, María M. (Society for Endocrinology, 2013)
      There is increasing evidence that proteins associated with lipid droplets (LDs) play a key role in the coordination of lipid storage and mobilization in adipocytes. The small GTPase, RAB18, has been recently identified as ...

    • Proteomic profiling of adipose tissue from Zmpste24(-/-) Mice, a model of Lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing 

      Peinado, Juan R.; Moral Quirós, Pedro; Pulido, Marina R.; Mariño García, Guillermo; Martínez-Chantar, M.L.; Vázquez Martínez, Rafael; Pérez Freije, José María; López Ontín, Carlos; Malagón, María M. (Science Direct, 2011)
      Lipodystrophy is a major disease involving severe alterations of adipose tissue distribution and metabolism. Mutations in genes encoding the nuclear envelope protein lamin A or its processing enzyme, the metalloproteinase ...

    • Rab18 drift in lipid droplet and endoplasmic reticulum interactions of adipocytes under obesogenic conditions 

      López-Alcalá, J.; Soler-Vázquez, M. Carmen; Tercero-Alcázar, C.; Sánchez Ceinos, Julia; Guzmán Ruiz, R.; Malagón, María M.; Gordon, Ana (MDPI, 2023)
      The adipose tissue stores excess energy in the form of neutral lipids within adipocyte lipid droplets (LDs). The correct function of LDs requires the interaction with other organelles, such as the endoplasmic reticulum ...

    • Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity 

      Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García-Navarro, Socorro; Gracia-Navarro, F.; Frühbeck, Gema; Vázquez Martínez, Rafael; Tinahones, Francisco J.; Malagón, María M.; López-Miranda, José (Public Libray of Science (PLOS), 2011)
      Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ...

    • Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity 

      Pulido, Marina R.; Díaz-Ruiz, Alberto; Jiménez-Gómez, Yolanda; García Navarro, S.; Gracia-Navarro, F.; Tinahones, Francisco J.; López-Miranda, José; Frühbeck, Gema; Vázquez Martínez, Rafael; Malagón, María M. (PLOS, 2011)
      Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing fat, the adipocytes. Proteomic analyses of LDs have consistently ...

    • Rab18 is reduced in pituitary tumors cusing acromegaly and its overexpression reverts growth hormone hypersecretion 

      Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Pulido, Marina R.; Jiménez Reina, L.; Quintero, Ana; Leal-Cerro, Alfonso; Soto, Alfonso; Webb, Susan M.; Sucunza, Nuria; Bartumeus, Frederic; Benito-López, Pedro; Galvez-Moreno, María A.; Castaño, Justo P.; Malagón, María M. (Oxford Academic, 2008)
      Context: Rab proteins regulate the sequential steps of intracellular membrane transport. Alterations of these GTPases and their associated proteins are emerging as the underlying cause for several human diseases involving ...

    • Sequential Exposure to Obesogenic Factors in Females Rats: From Physiological Changes to Lipid Metabolism in Liver and Mesenteric Adipose Tissue 

      Novelle, Marta G.; Vázquez, María J.; Peinado, Juan R.; Martinello, Kátia D.; López, Miguel; Luckman, Simon M.; Tena-Sempere, Manuel; Malagón, María M.; Nogueiras, Rubén; Diéguez, Carlos (Nature Research, 2017)
      During their lifetime, females are subjected to different nutritional and hormonal factors that could increase the risk of obesity and associated comorbidities. From early postnatal periods until the postmenopausal phase, ...