• Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases 

      Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Limia-Pérez, Laura; Romero-Cabrera, Juan Luis; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2020)
      Apart from its main function in the mitochondria as a key element in electron transport, Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant action in the generation of signals and the ...
    • Comparative of transcranial magnetic stimulation and other treatments in experimental autoimmune encephalomyelitis 

      Medina Fernández, Francisco Javier; Escribano, Begoña M.; Luque, Evelio; Caballero-Villarraso, Javier; Gómez-Chaparro, José L.; Feijóo, Montserrat; García-Maceira, Fé I.; Pascual-Leone, Álvaro; Drucker Colín, René Raúl; Túnez, Isaac (Elsevier, 2018)
      The effects of transcranial magnetic stimulation (TMS), natalizumab (nata), dimethyl fumarate (DMF) and dexamethasone (DEX) on clinical score and oxidative stress produced by a single dose of myelin oligodendrocyte ...
    • Effect of the combination of different therapies on oxidative stress in the experimental model of multiple sclerosis 

      Escribano, Begoña M.; Muñoz Jurado, Ana; Luque, Evelio; Galván, Alberto; Latorre, Manuel; Caballero-Villarraso, Javier; Giraldo, Ana I.; Agüera, Eduardo; Túnez, Isaac (IBRO, 2023)
      Oxidative stress is heavily involved in several pathological features of Multiple Sclerosis (MS), such as myelin destruction, axonal degeneration, and inflammation. Different therapies have been shown to reduce the oxidative ...
    • Glomerular Hematuria: Cause or Consequence of Renal Inflammation? 

      Moreno, Juan Antonio; Sevillano, Ángel; Gutiérrez, Eduardo; Guerrero-Hue, Melania; Vázquez-Carballo, Cristina; Yuste, Claudia; Herencia, Carmen; García-Caballero, Cristina; Praga, Manuel; Egido, J. (MDPI, 2019)
      Glomerular hematuria is a cardinal symptom of renal disease. Glomerular hematuria may be classified as microhematuria or macrohematuria according to the number of red blood cells in urine. Recent evidence suggests a ...
    • Olive Oil and the Hallmarks of Aging 

      Fernández del Río, Lucía; Gutiérrez-Casado, Elena; Varela-López, Alfonso; Villalba, José Manuel (MDPI, 2016)
      Aging is a multifactorial and tissue-specific process involving diverse alterations regardedas the “hallmarks of aging”, which include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, ...
    • Protective Role of Nrf2 in Renal Disease 

      Guerrero-Hue, Melania; Rayego-Mateos, Sandra; Vázquez-Carballo, Cristina; Palomino-Antolín, Alejandra; García-Caballero, Cristina; Opazo-Ríos, Lucas; Morgado-Pascual, José Luis; Herencia, Carmen; Mas, Sebastián; Ortiz, Alberto; Rubio-Navarro, Alfonso; Egea, Javier; Villalba, José Manuel; Egido, J.; Moreno, Juan Antonio (MDPI, 2020)
      Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ...
    • Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury 

      Vázquez-Carballo, Cristina; Herencia, Carmen; Guerrero-Hue, Melania; García-Caballero, Cristina; Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Opazo-Ríos, Lucas; González-Guerrero, Cristian; Vallejo-Mudarra, Mercedes; Cortegano, Isabel; Gaspar, María Luisa; Andrés, Belén de; Egido, J.; Moreno, Juan Antonio (Wiley, 2022)
      Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, ...