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Protective Role of Nrf2 in Renal Disease
(MDPI, 2020)
Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted to become by 2040 the fifth global cause of death. CKD is characterized by increased oxidative stress and chronic inflammation. ...
Toll-Like Receptors in Acute Kidney Injury
(MDPI, 2021)
Acute kidney injury (AKI) is an important health problem, affecting 13.3 million individuals/year. It is associated with increased mortality, mainly in low- and middle-income countries, where renal replacement therapy is ...
Hematuria Is Associated with More Severe Acute Tubulointerstitial Nephritis
(MDPI, 2020)
Acute tubulointerstitial nephritis (ATIN) is a common cause of acute kidney injury. Although haematuria is a risk factor for the development of renal disease, no previous study has analyzed the significance of haematuria ...
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury
(Wiley, 2022)
Massive intravascular hemolysis is a common characteristic of several pathologies. It is associated with the release of large quantities of heme into the circulation, promoting injury in vulnerable organs, mainly kidney, ...