Listar Departamento de Bioquímica y Biología Molecular por autor "943320a3-ce15-4b2f-b48c-f20e5e1fbf6e"
Mostrando ítems 1-9 de 9
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Application of iTRAQ reagent to relatively quantify the reversible redox state of cysteines
McDonagh, B.; Padilla, A.; Bárcena Ruiz, José Antonio (Universidad de Córdoba, Servicio de Publicaciones, 2010) -
Deficiency of Parkinson’s Related Protein DJ-1 Alters Cdk5 Signalling and Induces Neuronal Death by Aberrant Cell Cycle Re-entry
López‑Grueso, María José; Padilla, Carmen Alicia; Bárcena Ruiz, José Antonio; Requejo Aguilar, Raquel (Springer, 2022)DJ-1 is a multifunctional protein involved in Parkinson disease (PD) that can act as antioxidant, molecular chaperone, protease, glyoxalase, and transcriptional regulator. However, the exact mechanism by which DJ-1 dysfunction ... -
Detection of redox modified proteins by gel-free proteomics
McDonagh, B.; Ogueta-Villarreal, Samuel; Padilla, A.; Lasarte, G.; Rodríguez-Ortega, Manuel J.; Bárcena Ruiz, José Antonio (Universidad de Córdoba, Servicio de Publicaciones, 2008) -
Identification of new immunoprotective surface protein vaccine candidates against streptococcus suis infection by proteomics
Gómez-Gascón, Lidia; Olaya-Abril, Alfonso; Jiménez-Munguía, I.; Luque-Moreno, Inmaculada; Tarradas-Iglesias, Carmen; Bárcena Ruiz, José Antonio; Rodríguez-Ortega, Manuel J. (Universidad de Córdoba, Servicio de Publicaciones, 2011) -
New clues to metabolic regulation through changes in the thiol redox proteome
Bárcena Ruiz, José Antonio; McDonagh, B.; Requejo, R.; Pedrajas, J.R.; Padilla, C.A. (Universidad de Córdoba, Servicio de Publicaciones, 2011) -
Nitrogen starvation induces extensive changes in the redox proteome of Prochlorococcus sp. strain SS120
McDonagh, B.; Domínguez-Martín, María A.; Gómez-Baena, Guadalupe; López-Lozano, Antonio; Díez, Jesús; Bárcena Ruiz, José Antonio; García-Fernández, José Manuel (Wiley, 2012)Very low nitrogen concentration is a critical limitation in the oligotrophic oceans inhabited by the cyanobacterium Prochlorococccus, one of the main primary producers on Earth. It is well known that nitrogen starvation ... -
Overcoming function annotation errors in the Gram-positive pathogen Streptococcus suis by a proteomics-driven approach
Rodríguez-Ortega, Manuel J.; Luque-Moreno, Inmaculada; Tarradas-Iglesias, Carmen; Bárcena Ruiz, José Antonio (BioMed Central, 2008)Background: Annotation of protein-coding genes is a key step in sequencing projects. Protein functions are mainly assigned on the basis of the amino acid sequence alone by searching of homologous proteins. However, fully ... -
Peroxiredoxin 6 Down-Regulation Induces Metabolic Remodeling and Cell Cycle Arrest in HepG2 Cells
López-Grueso, María José; Tarradas Valero, Rosa María; Carmona Hidalgo, Beatriz; Lagal Ruiz, Daniel; Peinado, José; McDonagh, B.; Requejo Aguilar, Raquel; Bárcena Ruiz, José Antonio; Padilla C., Alicia (MDPI, 2019)Peroxiredoxin 6 (Prdx6) is the only member of 1-Cys subfamily of peroxiredoxins in human cells. It is the only Prdx acting on phospholipid hydroperoxides possessing two additional sites with phospholipase A2 (PLA2) and ... -
Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells
López-Grueso, María José; González, Raúl; Muntané Relat, Jordi; Bárcena Ruiz, José Antonio; Padilla, Alicia (MDPI, 2019)Sorafenib is the first-line recommended therapy for patients with advanced hepatocarcinoma (HCC) in de-differentiation stage (presenting epithelial–mesenchymal transition, EMT). We studied the role of the thioredoxin system ...