ListarProducción Científica por tema "DNA"
Mostrando ítems 1-14 de 14
-
A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine
(Oxford University Press, 2011)DNA cytosine methylation (5-meC) is a widespread epigenetic mark associated to gene silencing. In plants, DEMETER-LIKE (DML) proteins typified by Arabidopsis REPRESSOR OF SILENCING 1 (ROS1) initiate active DNA demethylation ... -
An AP Endonuclease Functions in Active DNA Demethylation and Gene Imprinting in Arabidopsis
(Public Library of Science, 2015)Active DNA demethylation in plants occurs through base excision repair, beginning with removal of methylated cytosine by the ROS1/DME subfamily of 5-methylcytosine DNA glycosylases. Active DNA demethylation in animals ... -
Biotecnología: una ciencia moderna para una institución centenaria
(Real Academia de Córdoba de Ciencias, Bellas Letras y Nobles Artes, 2011)Biotecnología es “toda aplicación tecnológica que utilice sistemas biológicos y organismos vivos o sus derivados para la creación o modificación de productos o procesos para usos específicos” (Convenio sobre Diversidad ... -
Caracterización genética de ganado bovino criollo argentino utilizando microsatélites
(Universidad de Córdoba, Servicio de Publicaciones, 1998)It is characterized a sample of Bovino Criollo Argentino cattle with a panel of eight microsatellites. It is detected a number of alleles between 2 and 7. The values of Heterocigosity by locus are between 0.46 for HEL-1 ... -
DNA demethylation through 5-methylcytosine excision. Molecular basis and potential applications
(Universidad de Córdoba, UCOPress, 2016)La metilación del DNA en el carbono 5 de la citosina (5-metilcitosina, 5-meC) es una marca epigenética estable, pero reversible, que promueve el silenciamiento génico y que desempeña un papel importante en el desarrollo ... -
Estudio con microsatélites de las principales variedades de ganado porcino del tronco ibérico
(Universidad de Córdoba, Servicio de Publicaciones, 2000)It is characterized a sample of 10 Iberian Pigs strains and one of Duroc with a panel of 25 microsatellites. It was detected a number of alleles between 4 and 20. The values of Heterocigosity by locus ranged between 0.03 ... -
Homologous Recombination Is Stimulated by a Decrease in dUTPase in Arabidopsis
(Public Library Of Science (PLOS), 2011)Deoxyuridine triphosphatase (dUTPase) enzyme is an essential enzyme that protects DNA against uracil incorporation. No organism can tolerate the absence of this activity. In this article, we show that dUTPase function is ... -
Identificación de proteínas que participan en una ruta de desmetilación activa de DNA en Arabidopsis thaliana
(Universidad de Córdoba, Servicio de Publicaciones, 2012)DNA methylation (5-methylcytosine, 5-meC) is an important epigenetic mark for transcriptional gene silencing that plays critical roles in regulation of developmental genes, genomic imprinting, X chromosome inactivation ... -
Promoter DNA Hypermethylation and Gene Repression in Undifferentiated Arabidopsis Cells
(Public Library of Science, 2008)Maintaining and acquiring the pluripotent cell state in plants is critical to tissue regeneration and vegetative multiplication. Histone-based epigenetic mechanisms are important for regulating this undifferentiated state. ... -
Role of beer in the modulation of degenerative processes. In vivo and in vitro integrative studies of the DNA protective activity, survival increase, antiproliferative potential and modulation of genetic methylation status
(Universidad de Córdoba, UCOPress, 2017)La dieta, entre otros factores del estilo de vida, es uno de los agentes medioambientales más importantes que ejercen efectos sobre la salud y sobre el riesgo de adquirir enfermedades (Bingham and Riboli 2004; Boffetta et ... -
ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion
(Oxford University Press, 2009)Arabidopsis ROS1 belongs to a family of plant 5-methycytosine DNA glycosylases that initiate DNA demethylation through base excision. ROS1 displays the remarkable capacity to excise 5-meC, and to a lesser extent T, ... -
Study and characterization of the Ph1 locus as tool to promote interspecific chromosome associations between wheat and barley species
(Universidad de Córdoba, UCOPress, 2015)Interspecific hybridization is used to introduce desirable characters from related species into allopolyploids such as wheat. The development of substitution and addition lines of related species in bread wheat can ... -
The DNA Repair Protein XRCC1 Functions in the Plant DNA Demethylation Pathway by Stimulating Cytosine Methylation (5-meC) Excision, Gap Tailoring, and DNA Ligation
(JBC, 2013)Background: Active DNA demethylation in plants is initiated by 5-meC DNA glycosylases of the ROS1/DME family and continued through a base excision repair pathway. Results: XRCC1 stimulates ROS1-initiated demethylation ...