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Role and regulation of the novel splicing variants sst5TMD4 and In1-ghrelin in breast cancer
(Universidad de Córdoba, UCOPress, 2016)
El cáncer, en sus múltiples formas, es uno de los mayores retos a los que se enfrenta la sociedad actual. Una de las mayores limitaciones en la investigación del cáncer es la gran heterogeneidad existente entre las diferentes ...
Functional role and therapeutic potential of the somatostatin and ghrelin systems and their splicing variants in prostate cancer
(Universidad de Córdoba, UCOPress, 2017)
El cáncer es una de las amenazas más serias y complejas para la salud de la población mundial1. En concreto, el cáncer de próstata es el segundo tipo de tumor solido más frecuente entre los hombres, y causa 300.000 muertes ...
Role of splicing process alterations in the appearance of endocrine-metabolic diseases and tumor pathologies
(Universidad de Córdoba, UCOPress, 2019)
Global human health is currently threatened by highly prevalent diseases such as obesity, diabetes and cancer. A common hallmark shared by these endocrine-metabolic and tumor diseases is the consistent alteration of the ...
Identification of novel cellular and/or molecular markers involved in the pharmacological response and contributions of splicing mechanisms in pituitary tumors
(Universidad de Córdoba, UCOPress, 2019)
Splicing Machinery is Dysregulated in Pituitary Neuroendocrine Tumors and is Associated with Aggressiveness Features
(MDPI, 2019)
Pituitary neuroendocrine tumors (PitNETs) constitute approximately 15% of all brain tumors, and most have a sporadic origin. Recent studies suggest that altered alternative splicing and, consequently, appearance of aberrant ...