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Identification of novel molecular markers and contribution of splicing mechanisms in endocrine-related tumoral pathologies
(Universidad de Córdoba, UCOPress, 2020)
Cancer represents one of the main challenges for the human being, in that it encompasses some of the most severe and health-threatening pathologies worldwide. Although great efforts are being implemented and significant ...
Identification of novel endocrine-metabolic and splicing machinery factors with diagnostic, prognostic and/or therapeutic potential in prostate cancer
(Universidad de Córdoba, UCOPress, 2020)
Prostate cancer (PCa) is the tumor pathology with the highest incidence among men in developed countries and represents one of the main causes of cancer-related death in this group. Despite the advances achieved during the ...
Implication of the alternative splicing process in the development of hepatocelular carcinoma
(Universidad de Córdoba, UCOPress, 2021)
Liver cancer represents a complex and heterogeneous pathology that encompasses several types of malignant tumors with unfavorable characteristics and prognosis, including hepatocellular carcinoma or hepatocarcinoma (HCC). ...
Identification of Novel Markers and Molecular Mechanisms with Diagnostic, Prognostic, and Therapeutic Potential in Brain Tumors
(Universidad de Córdoba, UCOPress, 2022)
Primary brain tumors represent a highly variable and heterogeneous group of neoplasms (~150 different types) that includes non-malignant and malignant tumors. The most frequent malignant brain tumors are gliomas (representing ...
Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer
(MDPI, 2020)
Certain components of the somatostatin-system play relevant roles in Prostate Cancer (PCa), whose most aggressive phenotype (Castration-Resistant-PCa (CRPC)) remains lethal nowadays. However, neuronostatin and the G ...
Identificación de la heterogeneidad molecular asociada a la enfermedad cardiovascular, la evolución clínica y la respuesta terapéutica en patologías Autoinmunes Sistémicas
(Universidad de Córdoba, UCOPress, 2022)
Las enfermedades autoinmunes son enfermedades multifactoriales, resultado de la interacción entre factores genéticos, factores ambientales y alteraciones del propio sistema inmune. Entre ellas, el lupus eritematoso sistémico ...
Molecular, cellular and anatomopathological study of oral cavity tumors
(Universidad de Córdoba, UCOPress, 2022)
Oral cavity squamous cell carcinoma (OSCC) continues to be an aggressive disease and a global challenge with a 5-year survival rate of 60%. Depending on the risk factors, surgery and adjuvant radiotherapy +/- chemotherapy ...
Identification of novel biomarkers and therapeutic targets in the pathological interaction between the dysregulation of the endocrinemetabolic system and prostate cancer
(Universidad de Córdoba, UCOPress, 2022)
Obesity (OB) is a metabolic chronic disease with a growing incidence and elevated morbidities and mortality [1, 2]. OB is also associated with elevated economic costs for the health systems representing a worldwide public ...