Listar DBCFI-Artículos, capítulos... por título

Mostrando ítems 26-45 de 178

    • Cannabidiol and Other Cannabinoids in Demyelinating Diseases 

      Navarrete, Carmen; García-Martín, Adela; Rolland, Alain; DeMesa, Jim; Muñoz, Eduardo (MDPI, 2021)
      A growing body of preclinical evidence indicates that certain cannabinoids, including cannabidiol (CBD) and synthetic derivatives, may play a role in the myelinating processes and are promising small molecules to be developed ...

    • CCN2 Binds to Tubular Epithelial Cells in the Kidney 

      Rayego-Mateos, Sandra; Morgado-Pascual, José Luis; Lavoz, Carolina; Rodrigues-Díez, Raúl R.; Márquez-Expósito, Laura; Tejera-Muñoz, Antonio; Tejedor-Santamaría, Lucía; Rubio-Soto, Irene; Marchant, Vanessa; Ruiz-Ortega, Marta (MDPI, 2022)
      Cellular communication network-2 (CCN2), also called connective tissue growth factor (CTGF), is considered a fibrotic biomarker and has been suggested as a potential therapeutic target for kidney pathologies. CCN2 is a ...

    • Ceruloplasmin and Coronary Heart Disease-A Systematic Review 

      Arenas de Larriva, Antonio P.; Limia-Pérez, Laura; Alcalá Díaz, Juan Francisco; Alonso, Álvaro; López-Miranda, José; Delgado-Lista, Javier (MDPI, 2020)
      Several studies indicate that oxidative stress might play a central role in the initiation and maintenance of cardiovascular diseases. It remains unclear whether ceruloplasmin acts as a passive marker of inflammation or ...

    • Changes in Splicing Machinery Components Influence, Precede, and Early Predict the Development of Type 2 Diabetes: From the CORDIOPREV Study 

      Gahete Ortiz, Manuel D.; Río Moreno, Mercedes del; Carpio Camargo, Antonio José; Alcalá Díaz, Juan Francisco; Alors-Pérez, Emilia; Delgado-Lista, Javier; Reyes Pupo, Oscar Gabriel; Ventura, Sebastián; Pérez Martínez, Pablo; Castaño, Justo P.; López Miranda, José; Luque, Raúl M. (Elsevier, 2018)
      Background: Type-2 diabetes mellitus (T2DM) is a major health problem with increasing incidence, which severely impacts cardiovascular disease. Because T2DM is associated with altered gene expression and aberrant splicing, ...

    • Characterization of the DNAM-1, TIGIT and TACTILE Axis on Circulating NK, NKT-Like and T Cell Subsets in Patients with Acute Myeloid Leukemia 

      Valhondo, Isabel; Hassouneh, Fakhri; López-Sejas, Nelson; Pera Rojas, Alejandra; Sánchez-Correa, Beatriz; Guerrero, Beatriz; Bergua, Juan M.; Arcos, María José; Bañas, Helena; Casas-Avilés, Ignacio; Sánchez García, Joaquín; Serrano, Josefina; Martín, Carmen; Durán, Esther; Alonso, Corona; Solana Lara, Rafael; Tarazona, Raquel (MDPI, 2020)
      Background: Acute myeloid leukemia (AML) remains a major clinical challenge due to poor overall survival, which is even more dramatic in elderly patients. TIGIT, an inhibitory receptor that interacts with CD155 and CD112 ...

    • Clinical Effectiveness and Safety of Once-Weekly GLP-1 Receptor Agonist Dulaglutide as Add-On to Metformin or Metformin Plus Insulin Secretagogues in Obesity and Type 2 Diabetes 

      Mirabelli, María; Chiefari, Eusebio; Tocci, Vera; Caroleo, Patrizia; Giuliano, Stefania; Greco, Emanuela; Luque, Raúl M.; Puccio, Luigi; Foti, Daniela Patrizia; Aversa, Antonio; Brunetti, Antonio (MDPI, 2021)
      Aims and methods: The aim of this monocentric retrospective observational study was to evaluate the 18-month safety and effectiveness of GLP-1 receptor agonist (GLP-1 RA) dulaglutide (DU) 1.5 mg/once weekly as an add-on ...

    • Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer 

      Jiménez-Vacas, J.M.; Gómez Gómez, Enrique; Montero-Hidalgo, Antonio J.; Herrero-Aguayo, V.; L-López, Fernando; Sánchez-Sánchez, Rafael; Guler, Ipek; Blanca, Ana; Méndez-Vidal, María José; Carrasco, Julia; López-Miranda, José; Requena-Tapia, M.J.; Castaño, Justo P.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2019)
      Recent data suggested that plasma Ghrelin O-Acyl Transferase enzyme (GOAT) levels could represent a new diagnostic biomarker for prostate cancer (PCa). In this study, we aimed to explore the diagnostic and prognostic/agg ...

    • CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals 

      Pera Rojas, Alejandra; Campos Fernández, Carmen; Sánchez-Correa, Beatriz; Tarazona, Raquel; Larbi, Anis; Solana Lara, Rafael; Alonso, Corona (Public Library of Science, 2014)
      Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in ...

    • Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases 

      Gutiérrez Mariscal, Francisco Miguel; Arenas de Larriva, Antonio P.; Limia-Pérez, Laura; Romero-Cabrera, Juan Luis; Yubero-Serrano, Elena M.; López-Miranda, José (MDPI, 2020)
      Apart from its main function in the mitochondria as a key element in electron transport, Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant action in the generation of signals and the ...

    • Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells 

      León González, A.J.; Sáez Martínez, Prudencio; Jiménez-Vacas, J.M.; Herrero-Aguayo, V.; Montero-Hidalgo, Antonio J.; Gómez Gómez, Enrique; Madrona, Andrés; Castaño, Justo P.; Espartero, José L.; Gahete Ortiz, Manuel D.; Luque, Raúl M. (MDPI, 2021)
      A high adherence to a Mediterranean diet has been related to numerous beneficial effects in human health, including a lower incidence and mortality of prostate cancer (PCa). Olive oil is an important source of phenolic ...

    • Comparative insights of the kisspeptin/kisspeptin receptor system: lessons from non-mammalian vertebrates 

      Tena-Sempere, Manuel; Felip, Alicia; Gómez, Ana; Zanuy, Silvia; Carrillo, Manuel (Elsevier, 2012)
      Kisspeptins, the peptide products of the Kiss1 gene, were initially identified in mammals as ligands of the G protein‐coupled receptor 54 (GPR54; also termed Kiss1R) with ability to suppress tumor metastasis. In late 2003, ...

    • Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport Chain Enzyme Activities Are Altered in n-3 Enriched fat-1 Mice 

      Hagopian, Kevork; Weber, Kristina L.; Hwee, Darren T.; Van Eenennaam, Alison L.; López-Lluch, Guillermo; Villalba, José Manuel; Burón, Isabel; Navas Lloret, Plácido; German, Bruce; Watkins, Steven; Chen, Yana; Wei, Alfreda; McDonald, Roger B.; Ramsey, Jon J. (Public Libray of Science (PLOS), 2010)
      The polyunsaturated nature of n-3 fatty acids makes them prone to oxidative damage. However, it is not clear if n-3 fatty acids are simply a passive site for oxidative attack or if they also modulate mitochondrial reactive ...

    • Consanguinidad en el toro de lidia 

      García Martín, J.; Alonso Moraga, F.; Rodero Franganillo, Antonio (Universidad de Córdoba, Servicio de Publicaciones, 1985)
      Five herds of fighting caatle were examined about the inbreeding. Inbreeding coefficients from pedigrees traced-back as far as seven ancestral generations were calculated. Also was ,obtained the variation coefficient and ...

    • Contribución al estudio de la anemia infecciosa en los équidos 

      Castejón Calderón, Francisco J. (Facultad de Veterinaria de Córdoba, 1944)

    • Covalent Immobilization of Antibodies through Tetrazine-TCO Reaction to Improve Sensitivity of ELISA Technique 

      García-Maceira, Tania; García-Maceira, Fé I.; González Reyes, José Antonio; Torres-Sánchez, Luis A.; Aragón-Gómez, Ana Belén; García-Rubiño, María Eugenia; Paz-Rojas, Elier (MDPI, 2021)
      Enzyme-linked immunosorbent assay (ELISA) is routinely used to detect biomolecules related to several diseases facilitating diagnosis and monitoring of these, as well as the possibility of decreasing their mortality rate. ...

    • Crohn’s Disease Increases the Mesothelial Properties of Adipocyte Progenitors in the Creeping Fat 

      Madeira, Ana; Serena, Carolina; Ejarque, Miriam; Maymó-Masip, Elsa; Millán, Mónica; Navarro-Ruiz, Carmen; Guzmán Ruiz, R.; Malagón, María M.; Espin, Eloy; Martí, Marc; Menacho, Margarita; Megía, Ana; Vendrell, Joan; Fernández-Veledo, Sonia (MDPI, 2021)
      Our understanding of the interplay between human adipose tissue and the immune system is limited. The mesothelium, an immunologically active structure, emerged as a source of visceral adipose tissue. After investigating ...

    • CYB5R3 overexpression preserves skeletal muscle mitochondria and autophagic signaling in aged transgenic mice 

      López Bellón, Sara; Rodríguez López, Sandra; González Reyes, José Antonio; Burón, Isabel; Cabo, Rafael de; Villalba, José Manuel (Springer, 2022)
      Cytochrome b5 reductase 3 (CYB5R3) overexpression activates respiratory metabolism and exerts prolongevity effects in transgenic mice, mimicking some of the salutary effects of calorie restriction. The aim of our study was ...

    • Desarrollo de un modelo docente adaptado a los criterios metodológicos 

      Ruiz, Antonio; Gaytán, Francisco; Lucena, Concepción; Villalba, José Manuel; Vázquez Martínez, Rafael; Martínez-Fuentes, Antonio J.; Gracia-Navarro, F.; González Reyes, José Antonio; García-Navarro, Socorro; Castaño, Justo P.; Alcaín Tejada, F.J.; Burón, Isabel; Malagón, María M. (Consejo Social de la Universidad de Córdoba, 2008)

    • Detrimental Effect of Cannabidiol on the Early Onset of Diabetic Nephropathy in Male Mice 

      Carmona Hidalgo, Beatriz; García-Martín, Adela; Muñoz, Eduardo; González-Mariscal, Isabel (MDPI, 2021)
      Anti-inflammatory and antidiabetogenic properties have been ascribed to cannabidiol (CBD). CBD-based medicinal drugs have been approved for over a lustrum, and a boom in the commercialization of CBD products started in ...

    • Diámetro del folículo preovulatorio y vesícula embrionaria en yeguas árabes y pura raza española 

      Vinuesa Silva, M.; Vivo-Rodríguez, R. (Universidad de Córdoba, Servicio de Publicaciones, 1993)
      An echographic study was made for the diameter evaluation of the preovulatory follicle and the embryonic vesicle at 20 days postfertili¬zation on 21 Arab Thoroughbred. mares and S I Spanish grouped in primiparous and ...