Listar Departamento de Ciencias Médicas y Quirúrgicas por título
Mostrando ítems 256-275 de 287
-
Terapia celular en el tratamiento de la miocardiopatía dilatada idiopática
(Universidad de Córdoba, UCOPress, 2015)Las miocardiopatías dilatadas (MCD) idiopáticas se definen como enfermedades del músculo cardiaco caracterizadas por las alteraciones en el tamaño de las cámaras cardíacas, en el grosor de la pared ventricular, o por una ... -
Técnica de la guía encarcelada en el tratamiento percutáneo de las bifurcaciones coronarias con stents: estudio aleatorrizado con microscopía estereoscopica
(Universidad de Córdoba, Servicio de Publicaciones, 2016)El tratamiento percutáneo de las lesiones coronarias en bifurcación constituye uno de los procedimientos terapéuticos de mayor complejidad técnica dentro de la cardiología intervencionista. El desarrollo de nuevas técnicas ... -
TGF-β Prevents Phosphate-Induced Osteogenesis through Inhibition of BMP and Wnt/β-Catenin Pathways
(Public Library of Science, 2014)Background: Transforming growth factor-b (TGF-b) is a key cytokine during differentiation of mesenchymal stem cells (MSC) into vascular smooth muscle cells (VSMC). High phosphate induces a phenotypic transformation of ... -
The APOB -516C/T polymorphism has no effect on lipid and apolipoprotein response following changes in dietary fat intake in a healthy population
(Elsevier, 2007)Our goal was to determine whether the presence of the −516C/T polymorphism in the APOB gene promoter modifies the lipid response to changes in the amount and quality of dietary fat. We studied 97 young healthy volunteers ... -
The Apolipoprotein E Gene Promoter (−219G/T) Polymorphism Determines Insulin Sensitivity in Response to Dietary Fat in Healthy Young Adults
(Elsevier, 2005)Insulin sensitivity (IS) is determined by genetic and environmental factors, including diet. The apoE gene promoter −219G/T polymorphism is associated with coronary heart disease and increased postprandial triacylglycerol-rich ... -
The clinical and molecular cardiometabolic fingerprint of an exploratory psoriatic arthritis cohort is associated with the disease activity and differentially modulated by methotrexate and apremilast
(Wiley, 2022)Objectives: (1) To evaluate clinical and molecular cardiovascular disease (CVD) signs and their relationship with psoriatic arthritis (PsA) features and (2) to identify a clinical patient profile susceptible to benefit ... -
The Combination of Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio with Liquid Biopsy Biomarkers Improves Prognosis Prediction in Metastatic Pancreatic Cancer
(MDPI, 2021)Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a highly inflammatory microenvironment and liquid biopsy has emerged as a promising tool for the noninvasive analysis of this tumor. In this study, plasma ... -
The dysbiosis of the bacterial population of the digestive system (intestinal microbiota) in patients with metabolic syndrome improves after two models of healthy diets: a diet rich in complex carbohydrates and a Mediterranean diet. CORDIOPREV study
(Universidad de Córdoba, UCOPress, 2017)The microbial community harbored in the human intestine, commonly known as the gut microbiota, is considered an organ fully integrated in the host which plays an important role in metabolism, physiology, nutrition and ... -
The Effect of Dietary Fat on LDL Size Is Influenced by Apolipoprotein E Genotype in Healthy Subjects
(American Society for Nutrition, 2004)LDL particle size is dependent on both genetic factors and environmental factors such as dietary fat composition. The apolipoprotein E (apoE) genotype is a major genetic determinant of LDL size. Thus, the aim of this work ... -
The gut microbiota pattern predictive for development of Metabolic Syndrome and dietary modulation
(Universidad de Córdoba, UCOPress, 2017)Introduction: The metabolic syndrome (MetS) is a condition characterized by a cluster of metabolic disorders including abdominal obesity, glucose intolerance, dyslipidemia and hypertension. The MetS is related with the ... -
The influence of the apolipoprotein E gene promoter (-219G/T) polymorphism on postprandial lipoprotein metabolism in young normolipemic males
(ASBMB, 2003)The apolipoprotein E (apoE) gene promoter (−219G/T) polymorphism has been associated with increased risk of myocardial infarction, premature coronary heart disease, and decreased plasma apoE concentrations. We examined ... -
The Metabolic Impact of Two Different Parenteral Nutrition Lipid Emulsions in Children after Hematopoietic Stem Cell Transplantation: A Lipidomics Investigation
(MDPI, 2022)Hematopoietic stem cell transplantation (HSCT) involves the infusion of either bone marrow or blood cells preceded by toxic chemotherapy. However, there is little knowledge about the clinical benefits of parenteral nutrition ... -
The relationship betwee pharmacological treatment and genetic polymorphism with clinical and structural severity ankylosing spondylitis
(Universidad de Córdoba, Servicio de Publicaciones, 2014)La espondilitis anquilosante (EA) se caracteriza por una estrecha relación entre la inflamación y los fenómenos de la formación de hueso cuyo despliegue es sólo parcialmente conocido. La característica de la enfermedad es ... -
The relationship between nutrients and biological aging
(Universidad de Córdoba, UCOPress, 2020)Introduction: Aging is a complex process significantly influenced by genetic background, as well as lifestyle factors, such as diet. A graduated senescence triggers various pathways like oxidative stress, systemic inflammation, ... -
The Role of Emotional Regulation and Affective Balance on Health Perception in Cardiovascular Disease Patients According to Sex Differences
(MDPI, 2020)One of the challenges of aging is the increase of people with chronic diseases, such as cardiovascular disease (CVD). Men and women experience the disease differently. Therefore, it has an impact on how CVD is treated and ... -
Transcriptomic Coordination in the Human Metabolic Network Reveals Links between n-3 Fat Intake, Adipose Tissue Gene Expression and Metabolic Health
(Public Library Of Science (PLOS), 2011)Understanding the molecular link between diet and health is a key goal in nutritional systems biology. As an alternative to pathway analysis, we have developed a joint multivariate and network-based approach to analysis ... -
Two independent apolipoprotein A5 haplotypes modulate postprandial lipoprotein metabolism in a healthy caucasian population
(Endocrine Society, 2007)Background: Apolipoprotein A5 (APOA5) plays an important role in plasma triacylglycerol (TG) homeostasis. Five polymorphisms (1131T>C, c.-3A>G, c.56C>G, IVS3+476G>A, and c.1259T>C) in the APOA5 gene define three common ... -
Uremic toxins induce THP-1 Monocyte endothelial adhesion and migration through specific miRNA expression
(MDPI, 2023)Atherosclerosis is initiated by the activation of endothelial cells that allows monocyte adhesion and transmigration through the vascular wall. The accumulation of uremic toxins such as indoxyl sulphate (IS) and p-cresol ... -
Utilidad de la determinación de parámetros de inflamación, estrés oxidativo y vitamina D como factores pronósticos en lactantes con bronquiolitis aguda
(Universidad de Córdoba, Servicio de Publicaciones, 2014)Introducción. La bronquiolitis aguda (BA) es la infección respiratoria aguda de las respiratorias inferiores más frecuente en los primeros años de la vida, constituyendo la principal causa de ingreso hospitalario en ... -
Utilidad del ecocardiograma transesofágico en pacientes jóvenes con bajo perfil cardioembólico
(Universidad de Córdoba, Servicio de Publicaciones, 2006)El ictus constituye una patología con un impacto social importante debido a su morbimortalidad. En pacientes jóvenes, en un alto porcentaje de los ictus no se llega a conocer la acusa (ictus criptogénico) y las posibilidades ...